SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen B.1.351 Mutation (South African Variant) (100 μg)

All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. Spike protein of the mutant strain B.1.351, also commonly known as the “South Africa Variant”. It is a full-length protein, which is active in its native trimeric form, that is stabilized in LMNG detergent.

B.1351_Datasheet

Features

Product Name: SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen (South African Variant)
WHO Reference: 501Y.V2/501.V2
UniProt Number: P0DTC2
SARS-CoV-2 Protein: South African Mutation B.1.351
Host: HEK293
Tag: C-terminal Rho1D4
Mutations that differ from SPIKE Protein: del 144, K417N, E484K, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H
Further Modifications: 

• Furin cleavage site “RRAR” mutated to “GSAG”; KV986PP
• C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence

Buffer Composition: 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001% LMNG
Molecular Weight: 1286 amino acids (including Rho1D4 tag and linker)/142.114 kDa