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SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen B.1.351 Mutation (South African Variant) (1 mg)

£2,600.00

1 mg

Product: BSV-COV-PR-63

All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. Spike protein of the mutant strain B.1.351, also commonly known as the “South Africa Variant”. It is a full-length protein, which is active in its native trimeric form, that is stabilized in LMNG detergent.

B.1351_Datasheet

Features

Product Name: SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen (South African Variant)
WHO Reference: 501Y.V2/501.V2
UniProt Number: P0DTC2
SARS-CoV-2 Protein: South African Mutation B.1.351
Host: HEK293
Tag: C-terminal Rho1D4
Mutations that differ from SPIKE Protein: del 144, K417N, E484K, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H
Further Modifications: 

  • Furin cleavage site “RRAR” mutated to “GSAG”; KV986PP
  • C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence

Buffer Composition: 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001% LMNG
Molecular Weight: 1286 amino acids (including Rho1D4 tag and linker)/142.114 kDa

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