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SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen B.1.1.7 Mutation (UK Variant) (100 μg)

£610.00

100 μg

Product: BSV-COV-PR-65

All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. Spike protein of the mutant strain B.1.1.7, also commonly known as the “UK Variant”. It is a full-length protein, which is active in its native trimeric form, that is stabilized in LMNG detergent.

B.1.1.7_Datasheet

Features

Product Name: SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen (UK Variant)
WHO Reference: SARS-CoV-2 VUI 202012/01
UniProt Number: P0DTC2
SARS-CoV-2 Protein: UK Mutation B.1.1.7
Host: HEK293
Tag: C-terminal Rho1D4
Mutations that differ from SPIKE Protein: del 69-70, del 144, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H
Further Modifications: 

  • Furin cleavage site “RRAR” mutated to “GSAG”; KV986PP
  • C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence

Buffer Composition: 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001% LMNG
Molecular Weight: 1286 amino acids (including Rho1D4 tag and linker), 142.114 kDa

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